Nurse Practitioner - Infectious Diseases

MUSC Health – Columbia Medical Center Downtown is seeking a compassionate and highly skilled Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join our growing Infectious Disease team. This is an exciting opportunity to practice in a collaborative environment focused on delivering exceptional care for patients with complex infectious diseases and conditions.

You’ll work alongside a collaborative, multidisciplinary team in a supportive environment that encourages innovation, professional growth, and work-life balance.

In this role, you will work closely with Infectious Disease physicians, hospital teams, and multidisciplinary specialists to provide comprehensive inpatient and outpatient care while contributing to improved patient outcomes and community health.

About MUSC Health – Columbia Medical Center Downtown:

MUSC Health – Columbia Medical Center Downtown is a full-service, community-based hospital located in the heart of Columbia, South Carolina. As part of the nationally recognized Medical University of South Carolina health system, the downtown campus is committed to delivering high-quality, patient-centered care supported by the innovation, research, and clinical expertise of one of the nation’s leading academic medical centers.

Providers at Columbia Medical Center Downtown benefit from a collaborative culture, access to advanced clinical resources, and the opportunity to care for a diverse patient population across the Midlands region.

Required Qualifications:

• Advanced Practice Provider: Nurse Practitioner (NP) or Physician Assistant (PA)
• Infectious Disease experience preferred, but motivated new graduates with strong clinical training are encouraged to apply
• Strong clinical assessment and diagnostic skills
• Passion for delivering patient-centered care in a collaborative team environment
• Commitment to evidence-based medicine, infection prevention, and quality improvement

Position Highlights:

• Provide inpatient and outpatient Infectious Disease follow-up care
• Evaluate and manage patients with acute and chronic infectious conditions including sepsis, bacteremia, osteomyelitis, hepatitis, and complex infections
• Collaborate with physicians, pharmacists, nursing staff, and care management teams to develop individualized treatment plans
• Assist with antimicrobial stewardship initiatives and infection prevention strategies
• Participate in patient education, transitions of care, and coordination with referring providers
• Utilize Epic EHR and integrated clinical tools to support efficient, high-quality patient care
• Join a supportive culture that values teamwork, provider wellness, and professional development

Benefits & Resources for Providers:

• Competitive compensation and benefits
• Employer-funded retirement plans
• Paid occurrence malpractice coverage
• Paid parental leave
• Epic EHR with provider-centered optimization and robust user support
• AI-enabled documentation and workflow tools integrated into Epic to reduce administrative burden and support clinical decision-making at the point of care
• Team-based care models that support sustainable workloads, shared responsibility, and provider well-being

Life in Columbia, South Carolina:

Discover the best of both worlds, big-city opportunity with small-town warmth.
Columbia is South Carolina’s vibrant capital city, perfectly positioned between the beautiful beaches of the Lowcountry and the majestic Blue Ridge Mountains. Enjoy top rated schools, family friendly neighborhoods, award winning restaurants, festivals, and endless outdoor adventures at Lake Murray and nearby state parks.         

About MUSC:

South Carolina’s leading academic health system, MUSC Health, serves patients across the state through a growing network of hospitals, clinics, and specialty services. As the clinical enterprise of the Medical University of South Carolina, MUSC Health integrates academic medicine, research, and education with a strong commitment to patient care. Providers who join MUSC Health become part of a mission-driven organization recognized for clinical excellence, innovation, and meaningful investment in providers’ success. With opportunities in both academic and community settings, MUSC Health provides the scale, resources, and infrastructure to support meaningful, long-term provider careers.

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.