Physician - Research

The Cleveland Clinic is establishing an innovative Center for Experimental Therapeutics whose vision is to be at the forefront of drug discovery and development. The Center is committed to pioneering new approaches that leverage cutting-edge technologies and accelerate the creation of novel therapeutics that address unmet medical needs. It is supported by the exceptional resources at the Cleveland Clinic.

We are seeking a highly motivated faculty member to join our dynamic team. The ideal candidate will have expertise in AI-based drug discovery (such as small molecules and biologics) and testing.  This is a unique growth opportunity to join a top-ranked medical center and contribute to groundbreaking research at the intersection of artificial intelligence and therapeutic innovation.

Key Responsibilities: 

• Develop and apply AI/ML models in multiple areas of therapeutic development including novel target identification as well as prediction and design of novel therapeutic biologics (such as antibodies and nanobodies) and/or small molecule compounds.
• Collaborate with interdisciplinary teams to integrate computational approaches with experimental validation.
• Secure research funding and lead projects in AI-driven drug discovery.
• Mentor graduate students and postdoctoral fellows, fostering a collaborative and innovative research environment.
• Publish high-impact research findings in peer-reviewed journals and present at scientific conferences.

Qualifications: 

• D. and/or M.D.(or equivalent in Computational Biology, Bioinformatics, Computer Science, Chemistry, or a related field.
• Demonstrated expertise in AI and machine learning techniques (such as deep learning, generative AI, foundation models) as applied to drug discovery.
• Strong publication record showcasing innovative research in AI and therapeutics.
• Excellent communication and teamwork skills, with a commitment to interdisciplinary collaboration.
• Experience in securing research funding and leading research projects is desirable.

What We Offer: 

• Access to state-of-the-art facilities and resources within a collaborative research environment at Cleveland Clinic.
• Opportunities for professional growth and development in a leading academic institution.
• Competitive salary and benefits package.

Cleveland Clinic

Cleveland Clinic has operated for over 100 years on the principle of bringing innovative teams together to advance patient care. Today, we are a world leader in science-based healthcare. Our strategic plan for research harnesses information technology to power significant advances in both personalized and population medicine. A major component of our strategy includes our anchor role in building the Cleveland Innovation District. This unprecedented collaboration includes participation and investment by the State of Ohio, along with five independent Cleveland healthcare and academic institutions and is designed to transform research, education, and economic opportunities in Northeast Ohio, the United States, and across the world.

Cleveland Clinic Research

Cleveland Clinic Research, a part of the global Cleveland Clinic enterprise, has a footprint spanning nearly 1 million square feet, with two new state-of-the-art facilities scheduled to open in 2026. In 2024, research funding grew to $520 million, which includes $176 million in federal funding across 632 federal awards. In addition, Cleveland Clinic’s global footprint provides a wealth of resources to support research throughout the enterprise, including our locations in Northeast Ohio, Florida, London, and Abu Dhabi.

Application Instructions:  

Interested candidates should submit the following to Kelsey Garcia, [email protected]: 

• A cover letter detailing your research interests and career goals.
• A curriculum vitae (CV).
• A statement of research plans (2-3 pages).
• Contact information for three professional references.